‘Hefty side-effects’: Tech millionaire Bryan Johnson drops ‘longevity drug’ from his mission to cheat death

MT HANNACH
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Bryan Johnson, “The Man Who Wants to Live Forever,” discovered a problem in his meticulous approach to cheating death. The 47-year-old tech millionaire, who tirelessly strives to defy aging, stopped taking a longevity drug, which could have done more harm than good.

Johnson recently revealed that he stopped taking rapamycin – and that might have done more harm than good.

The tech millionaire consumed 13 milligrams of the immunosuppressant rapamycin every two weeks, a drug that transplant patients take to help prevent organ rejection.

In a new Netflix documentary about him, “Don’t Die: The Man Who Wants to Live Forever,” Johnson called his routine “the most aggressive rapamycin protocol of any in the industry.”

Johnson said he experimented with rapamycin for nearly five years, until the end of September. He admitted in November that he had dropped the cancer drug from his strict diet.

“Despite the immense potential of preclinical trials, my team and I have concluded that the benefits of lifelong treatment with rapamycin do not justify the significant side effects,” he added.

Johnson said he suffered occasional skin and soft tissue infections, abnormal levels of fats in his blood, elevated blood sugar and a higher resting heart rate.

“With no other underlying causes identified, we suspected rapamycin, and because dosage adjustments had no effect, we decided to stop it completely,” Johnson explained.

The U.S. Food and Drug Administration (FDA) has not approved rapamycin for anti-aging treatment, but doctors prescribe it off-label because it has been shown to extend the healthy lifespan of mouse.

The former Silicon Valley executive said preclinical and clinical research indicated that prolonged use of rapamycin could disrupt lipid metabolism and induce insulin and glucose intolerance.

“Longevity research around these investigational compounds is constantly evolving, requiring continued and close observation of the research and my biomarkers, which my team and I are constantly doing,” he added.

Johnson spends $2 million a year on medical diagnostics and treatments, combined with a meticulously crafted regimen of diet, sleep and exercise to see if he can slow, and perhaps even reverse, the aging process.

A few months ago, the tech millionaire revealed that he had undergone a total plasma exchange in which the fluid in his body was replaced with pure albumin, a protein found in the blood plasma of a woman. person. He stressed that the process was different from when he exchanged blood with his teenage son.

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